منابع مشابه
Protective immunity induced in mice by F8.1 and F8.2 antigens purified from Schistosoma mansoni eggs.
Schistosoma mansoni soluble egg antigens (SEA) were fractionated by isoelectric focusing, resulting in 20 components, characterized by pH, absorbance and protein concentration. The higher absorbance fractions were submitted to electrophoresis, and fraction 8 (F8) presented a specific pattern of bands on its isoelectric point. Protein 3 was observed only on F8, and so, it was utilized to rabbit ...
متن کاملHuman immune responses to Schistosoma mansoni vaccine candidate antigens.
To determine the naturally occurring immunological responses to the Schistosoma mansoni antigens paramyosin, IrV-5, Sm-23 (MAP-3), and triose phosphate isomerase (MAP-4), a total of 119 subjects from an area of endemicity for schistosomiasis, including "resistant" subjects (n = 17) were evaluated. Specific immunoglobulin G1 (IgG1), IgG2, IgG3, IgG4, and IgA levels for each of the antigens and t...
متن کاملDrug-Induced Exposure of Schistosoma mansoni Antigens SmCD59a and SmKK7
BACKGROUND Schistosomiasis is a serious health problem especially in developing countries and affects more than 243 million people. Only few anthelmintic drugs are available up to now. A major obstacle for drug treatment is the different developmental stages and the varying host compartments during worm development. Anthelmintic drugs have been tested mainly on adult schistosomes or freshly tra...
متن کاملPotency of detergents in enhancing Schistosoma mansoni tegumental antigens.
INTRODUCTION Vaccine strategies represent an essential component for the future control of schistosomiasis. This work aimed to evaluate the role of detergents for potentiating the effect of Schistosoma mansoni tegumental antigens (TA) against challenge infection. METHODOLOGY Two detergents; Triton X-100 (TX-100) and sodium dodecyl sulfate (SDS), were selected for extraction of tegumental prot...
متن کاملSchistosoma mansoni cercaria and schistosomulum antigens in serodiagnosis of schistosomiasis.
Schistosoma mansoni cercaria and schistosomulum obtained in vitro were used in immunofluorescence (IF) tests and indirect hemagglutination (IHA) tests of 137 study sera, 44 from subjects infected with S. mansoni and 93 from healthy subjects residing outside areas endemic for the disease. The results of these tests were compared with those obtained by testing the same sera using conventional adu...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1987
ISSN: 0074-0276
DOI: 10.1590/s0074-02761987000800021